2 Sep 2014

New Study Reveals Sugar Doesn't Just Feed But Causes Cancer

A groundbreaking new study, uncovered by one of our volunteer researchers at Greenmedinfo – Jonathan Middleton – is the first of its kind to identify sugar, not only as fuel source for an already existing cancer, but as a primary driver in oncogenesis – i.e. the initiation of cancerous characteristics (phenotype) within previously healthy cells.
Published in the Journal of Cliinical Investigation and titled, Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways, researchers addressed a common perception (or misperception) in the cancer research community regarding sugar's relationship to cancer: namely, "increased glycolysis [sugar based metabolis] is frequently viewed as a consequence of oncogenic events that drive malignant cell growth and survival."

Contrary to this conventional view, the new study "provide[s] evidence that increased glycolytic activation itself can be an oncogenic event..." That is to say, the activation of sugar-based metabolism in a cell – driven by both the presence of increased quantities of glucose and the increase glucose receptors on the cell membrane surface (i.e. "overexpression of a glucose transporter") – drives cancer initiation.

Moreover, the study found that "Conversely, forced reduction of glucose uptake by breast cancer cells led to phenotypic reversion." In other words, interfering with sugar availability and uptake to the cell causes the cancer cell to REVERSE towards its pre-cancer structure-function (phenotype)........

Not good for teeth either.

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